Choice of a Measles Vaccine

Abstract

WITH the multiplying of available vaccines against measles and the increasing number of reports by clinical investigators concerning these vaccines and their methods of administration, practitioners and public-health officers have expressed confusion and uncertainty about the best procedures for such immunization. On the basis of recent evidence the use of inactivated vaccine alone, or inactivated vaccine followed by live, attenuated measles-virus vaccine, appears inadvisable as a routine procedure. Regarding the inactivated vaccine alone, the precipitous drop of neutralizing antibodies to nondetectable levels in vaccinated persons even after 3 doses of vaccine,^{1 , 2} together with the occurrence of natural measles —that is, . . .