The Effect of the Calcium Hydroxide-Calcium Aluminate Antibody Purification Procedure on the Physical Properties of Rabbit Gamma Globulin
- 1 September 1951
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 67 (3), 207-212
- https://doi.org/10.4049/jimmunol.67.3.207
Abstract
The calcium hydroxide-calcium aluminate treatment used for the purification of antiprotein antibody has been applied to rabbit gamma globulin, and its effect on molecular structure followed by electrophoretic, sedimentation and viscosity measurements. No appreciable alteration occurred when the treatment was carried out at pH 11.4; at pH 12.6 some unfolding of the molecule occurred.Keywords
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