Resistance of Shigella dysenteriae Type 1 to Ampicillin and Other Antimicrobial Agents: Strains Isolated during a Dysentery Outbreak in a Hospital in Mexico City
- 1 May 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 133 (5), 572-575
- https://doi.org/10.1093/infdis/133.5.572
Abstract
In June 1972, an epidemic of dysentery began in a hospital ward lodging 22 children with tuberculosis. Fifteen of them developed the disease and five children died. The age of the children ranged from five months to four years. A rectal swab culture taken from all hospitalized children three weeks after the initiation of the outbreak revealed Shigella dysenteriae type 1 in five of the patients (28%). The strains isolated were susceptible to cephalothin, gentamicin, kanamycin, colistin, trimethoprim, and nalidixic acid, but were resistant to ampicillin (Escherichia coli K-12 indicated that these strains were infected with two different plasmids; one was responsible for resistance to chloramphenicol, tetracycline, streptomycin, and sulfonamides, and the other caused resistance to ampicillin. The epidemiological and clinical importance of these findings is emphasized.This publication has 3 references indexed in Scilit:
- Transferable Antibiotic Resistance Associated with an Outbreak of ShigellosisAnnals of Internal Medicine, 1967
- ANTIBIOTIC SUSCEPTIBILITY TESTING BY A STANDARDIZED SINGLE DISK METHOD1966
- Studies of Diarrheal Disease in Central America *The American Journal of Tropical Medicine and Hygiene, 1965