Hypothalamic-Adenohypophyseal Function in Male Rhesus Monkeys

Abstract
The secretion of six anterior pituitary hormones in both the basal state and after stimulation or suppression in nine young adult male rhesus monkeys (Macaco mulatta) was studied. Growth hormone (GH), prolactin, thyroid-stimulating hormone (TSH), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) secretion were evaluated. Adrenocorticotropin hormone (ACTH) secretion was studied indirectly by measuring plasma cortisol levels. The tests were performed in combination and in sequence over a 7-hour period. Thus, multiple functions of the hypothalamic-hypophyseal axis can be studied quickly utilizing small quantities of blood.