MOLECULAR INTERACTION OF ISOALLOXAZINE DERIVATIVES

Abstract

Interaction in water solution between isoalloxazine derivatives and various conjugated molecules has been studied. The results obtained argue against hydrogen bonding between interactant and isoalloxazine as a primary feature of interaction in the systems examined and suggest that molecular charge transfer may be a more important factor. Alternative interpretations are possible. The data are discussed in relation to current concepts of the interaction of isoalloxazine with proteins and with other compounds of biochemical interest.