Growth and death in overagitated microcarrier cell cultures
- 5 February 1989
- journal article
- research article
- Published by Wiley in Biotechnology & Bioengineering
- Vol. 33 (6), 731-744
- https://doi.org/10.1002/bit.260330611
Abstract
The effects of hydrodynamic forces on cell growth are investigated for animal cells growing on microcarriers. A reduction in net growth was observed with high levels of agitation. DNA measurements indicated that the reduction in net growth was due entirely to cell death, from hydrodynamic forces. No inhibition or enhancement of cell replication appeared to occur with high levels of agitation.This publication has 39 references indexed in Scilit:
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