COMPARATIVE PATHOGENICITY OF CANDIDA ALBICANS FOR MICE AND RABBITS

Abstract

Ten strains of Candida albicans isolated from human sources were studied. The results indicate that the mortality rates are as high or higher in mice than in rabbits. These conclusions are based on comparative weight for weight studies following intravenous inoculation in both species of laboratory annals. Other species of Candida were used as controls. Candida tropicalis, however, showed some lethality for mice, but not for rabbits. Candida parapsilosis, and Candida stellatoidea did not produce death in mice or rabbits. Candida guilliermondii, Candida krusei, and Candida pseudotropicalis had no lethal effects on mice.