A growth-limiting, mild zinc-deficiency syndrome in some southern Ontario boys with low height percentiles

Abstract

A double-blind, pair-matched 12-mo study examined the effects of a zinc supplement (10 mg Zn/d as ZnSO4) on linear growth, taste acuity, attention span, biochemical indices, and energy intakes of 60 boys (aged 5–7 y) with height less than or equal to 15th and midparent height greater than 25th percentiles. Boys with initial hair Zn less than 1.68 mumol/g (n = 16) had a lower mean (+/- SD) weight-for-age Z score (-0.44 +/- 0.59 vs -0.08 +/- 0.84), and a higher median recognition threshold for salt (15 vs 7.5 mmol; p = 0.02) than those with hair Zn greater than 1.68 mumol/g. Only boys with hair Zn less than 1.68 mumol/g responded to the Zn supplement with a higher mean change in height-for-age Z score (p less than 0.05); taste acuity, energy intakes, and attention span were unaffected. A growth-limiting Zn deficiency syndrome exists in boys with low height percentiles, hair Zn levels less than 1.68 mumol/g, and impaired taste acuity.