Thrombotic Thrombocytopenic Purpura in Pregnancy
- 18 May 1963
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 184 (7), 587-590
- https://doi.org/10.1001/jama.1963.73700200008025a
Abstract
THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP) is being diagnosed with increasing frequency. Five cases have been reported in which the disease occurred as a complication of pregnancy.1-4 We are here presenting a synopsis of these cases and are adding a sixth case together with a discussion of diagnosis and management. Report of a Case On Jan 20, 1961, a 28-yr-old pregnant woman, Gravida 6, Para 4, whose expected date of confinement was Feb 20, came to The Bronx Hospital in active labor. Fifteen minutes after admission a 4 lb 6 oz (2.0 kg) girl was delivered spontaneously. Intrapartum bleeding was estimated at less than 150 cc. The only notable signs at this time were pallor (Table 1) and a blood pressure of 140/90 mm Hg. A blood transfusion had to be discontinued after 800 cc because of a chill and vomiting. Rectal temperature was 100 F (37.8 C) and pulse rateKeywords
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- HEMOSTATIC DEFECTS AND INCREASED RED CELL DESTRUCTION IN PREECLAMPSIA AND ECLAMPSIA1954
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