RADIOIODINE EQUILIBRIUM STUDIES OF THYROID AND BLOOD
- 1 February 1961
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 68 (2), 309-316
- https://doi.org/10.1210/endo-68-2-309
Abstract
A method of isotope equilibrium has been used to study iodinated amino acids of thyroid and blood in the rat. Iodide, monoiodotyrosine, diiodotyrosine, thyroxine and 3′,3,5-triiodothyronine were found to comprise 13%, 20%, 46%, 18%, and 3% of the thyroidal iodine respectively. Thyroxine accounted for approximately 80% of the blood iodine, triiodothyronine 3.5% and the iodinated tyrosines from zero to 4%. These figures are consistent with the hypothesis than in the rat, thyroxine and triiodothyronine contribute approximately half each of the total physiological activity of the thyroid hormones.Keywords
This publication has 22 references indexed in Scilit:
- THE EFFECT OF LOW IODINE DIET ON THYROID FUNCTION IN THE RAT*†Journal of Clinical Endocrinology & Metabolism, 1952
- NATURE OF PLASMA IODINE FOLLOWING DESTRUCTION OF THE RAT THYROID WITH I131Journal of Biological Chemistry, 1952
- Sur la déshalogénation enzymatique des iodotyrosines par le corps thyroïde et sur son rôle physiologiqueBiochimica et Biophysica Acta, 1952
- NON-THYROGLOBULIN IODINE OF THE THYROID GLAND .2. INORGANIC IODIDE1951
- THE NATURE OF THE CIRCULATING THYROID HORMONE IN GRAVES' DISEASE 1JCI Insight, 1951
- THE MONOIODOTYROSINE CONTENT OF THE THYROID GLANDJournal of Biological Chemistry, 1950
- Nature of the Circulating Thyroid HormoneNature, 1949
- THE NATURE OF THE CIRCULATING THYROID HORMONEJournal of Biological Chemistry, 1948
- Dosage colorimétrique de la thyroxine, de la diiodotyrosine et de la monoiodotyrosine. application aux protéines iodéesBiochimica et Biophysica Acta, 1947
- Observations on the iodine-containing compounds of the thyroid gland. Isolation of dl-3:5-di-iodotyrosineBiochemical Journal, 1929