Primer Unblocking and Rescue of DNA Synthesis by Azidothymidine (AZT)-resistant HIV-1 Reverse Transcriptase
Open Access
- 1 May 2002
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (21), 18611-18618
- https://doi.org/10.1074/jbc.m110836200
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Antiretroviral Therapy in AdultsJAMA, 2000
- Pre-Steady-State Kinetic Characterization of Wild Type and 3‘-Azido-3‘-deoxythymidine (AZT) Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Implication of RNA Directed DNA Polymerization in the Mechanism of AZT ResistanceBiochemistry, 1997
- Single-Step Kinetics of HIV-1 Reverse Transcriptase Mutants Responsible for Virus Resistance to Nucleoside Inhibitors Zidovudine and 3-TCBiochemistry, 1997
- [25] Analysis of inhibition of retroviral reverse transcriptaseMethods in Enzymology, 1996
- Sensitivity of HIV-1 Reverse Transcriptase and Its Mutants to Inhibition by Azidothymidine TriphosphateBiochemistry, 1994
- Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidineAntimicrobial Agents and Chemotherapy, 1994
- Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine.Proceedings of the National Academy of Sciences, 1992
- Multiple Mutations in HIV-1 Reverse Transcriptase Confer High-Level Resistance to Zidovudine (AZT)Science, 1989
- HIV with Reduced Sensitivity to Zidovudine (AZT) Isolated During Prolonged TherapyScience, 1989
- Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase.Proceedings of the National Academy of Sciences, 1986