Induction of the “Pregnancy Zone” Protein by Conjugated Oestrogens

Abstract

Treatment with conjugated estrogens significantly increased the serum concentration of the pregnancy zone protein (PZ) in a group of postmenopausal women. The basic level of PZ before treatment was comparatively high in this group of women and might be related to age and previous pregnancies. Naturally occurring conjugated estrogens have a similar effect on the induction of PZ as synthetic estrogens.