Location and function of linker histones
- 1 December 1998
- journal article
- Published by Springer Nature in Nature Structural & Molecular Biology
- Vol. 5 (12), 1025-1028
- https://doi.org/10.1038/4133
Abstract
The linker histones, H1 and its variant forms, have been implicated in the formation of higher orders of chromatin structure and gene repression. Three recent manuscripts have reexamined the location of H1 within the nucleosome particle and its function in the regulation of transcription.Keywords
This publication has 36 references indexed in Scilit:
- Differential nucleosome positioning on Xenopus oocyte and somatic 5 s RNA genes determines both TFIIIA and H1 binding: a mechanism for selective H1 repressionJournal of Molecular Biology, 1998
- Position and orientation of the globular domain of linker histone H5 on the nucleosomeNature, 1998
- Role of Histone H1 as an Architectural Determinant of Chromatin Structure and as a Specific Repressor of Transcription onXenopus Oocyte 5S rRNA GenesMolecular and Cellular Biology, 1998
- Crystal structure of the nucleosome core particle at 2.8 Å resolutionNature, 1997
- Where is the globular domain of linker histone located on the nucleosome?Trends in Biochemical Sciences, 1997
- Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5Nature, 1993
- Crystal structure of globular domain of histone H5 and its implications for nucleosome bindingNature, 1993
- Histone H1 and the regulation of transcription of eukaryotic genesTrends in Biochemical Sciences, 1990
- Assembly and propagation of repressed and derepressed chromosomal statesCell, 1985
- Studies on the Role and Mode of Operation of the Very‐Lysine‐Rich Histone H1 in Eukaryote ChromatinEuropean Journal of Biochemistry, 1977