Design, Synthesis, and Evaluation of the First Mechanism-Based Inhibitor of Glucosamine 6-Phosphate Synthase
- 1 June 1997
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 119 (24), 5748-5749
- https://doi.org/10.1021/ja970254t
Abstract
No abstract availableThis publication has 21 references indexed in Scilit:
- Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: evidence from the 1.8 å crystal structure of the glutaminase domain of glucosamine 6-phosphate synthaseStructure, 1996
- Mechanism-based inactivation of ribonuclease AThe Journal of Organic Chemistry, 1995
- Glutamate .gamma.-Semialdehyde as a Natural Transition State Analog Inhibitor of Escherichia coli Glucosamine-6-phosphate SynthaseBiochemistry, 1995
- Synthesis and biological activities of peptides containing N3-(S)-2-bromosuccinamoyl-(S)-2,3-diaminopropanoic acidEuropean Journal of Medicinal Chemistry, 1994
- Actions of Antiulcer DrugsScience, 1993
- Concise, Stereocontrolled Synthesis of the C4 Epimers of Anticapsin and Bacilysin: Revision of the Configurations of the Natural ProductsAustralian Journal of Chemistry, 1993
- Molecular cloning and overexpression of the glucosamine synthetase gene from Escherichia coliBiochimie, 1988
- Inactivation of glucosamine-6-phosphate synthetase from Salmonella typhimurium LT2 by fumaroyl diaminopropanoic acid derivatives, a novel group of glutamine analogsBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1986
- A novel peptide delivery system involving peptidase activated prodrugs as antimicrobial agents. Synthesis and biological activity of peptidyl derivatives of 5-fluorouracilJournal of Medicinal Chemistry, 1984
- The inactivation of glucosamine synthetase from bacteria by anticapsin, the C-terminal epoxyamino acid of the antibiotic tetaineBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1984