Nature of the Scrapie Agent: Evidence Against a Viroid
- 1 November 1974
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 14 (5), 1099-1103
- https://doi.org/10.1128/jvi.14.5.1099-1103.1974
Abstract
The postulated viroid nature of scrapie agent was tested. Since the agent could not be recovered after a carefully controlled phenol extraction of infected mouse brains, it is suggested that this agent is not a viroid.Keywords
This publication has 14 references indexed in Scilit:
- Potato spindle tuber viroidVirology, 1973
- Reconstitution of 50S Ribosomal Subunits from Dissociated Molecular ComponentsNature, 1970
- Further studies of the infectivity and stability of extracts and homogenates derived from scrapie affected mouse brainsJournal of Comparative Pathology, 1969
- Scrapie : A modified membrane hypothesisJournal of Theoretical Biology, 1968
- Potato Spindle Tuber Virus: A Plant Virus with Properties of a Free Nucleic AcidScience, 1967
- Nature of the Scrapie Agent: Self-replication and ScrapieNature, 1967
- Nature of the Scrapie AgentNature, 1967
- Attempts to release the scrapie agent from tissue debrisJournal of Comparative Pathology, 1967
- The exceptionally small size of the scrapie agentBiochemical and Biophysical Research Communications, 1966
- ENCEPHALOPATHY IN MICE PRODUCED BY INOCULATION WITH SCRAPIE BRAIN MATERIALThe Lancet, 1961