Effects of gastrointestinal hormones on the growth of human intestinal epithelial cells in vitro.
- 1 May 1989
- Vol. 30 (5), 600-604
- https://doi.org/10.1136/gut.30.5.600
Abstract
The growth of cultured epithelium like cells from human normal embryonic intestine was studied in response to various hormones using a method that quantifies the number of cells by the amount of dye that they bind after fixation. Gastrin and neurotensin in the pg/ml range and higher caused small increases in cell growth. Glucagon and VIP were stimulatory in the low ng/ml range, whereas somatostatin and bombesin had no effect at the lower concentrations but were stimulatory at the highest concentration tested (10 and 100 ng/ml respectively). Secretin and pancreozymin (cholecystokinin) seemed to be ineffective.This publication has 35 references indexed in Scilit:
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