Leucylglycinamide Released from Oxytocin by Human Uterine Enzyme
- 27 August 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 173 (3999), 827-829
- https://doi.org/10.1126/science.173.3999.827
Abstract
Uteri of pregnant and nonpregnant women contain enzymic activities which inactivate oxytocin. A potent enzyme, which has been partially purified from uterine homogenates, cleaves the prolyl-leucyl peptide bond of oxytocin. This findinig associates for the first time the release of the dipeptide leucylglycinamide with the degradation of neurohypophyseal hormones.Keywords
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