Hydroxylation in vitro of pharmacologically active phenothiazine derivatives
- 1 May 1964
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 16 (5), 342-346
- https://doi.org/10.1111/j.2042-7158.1964.tb07467.x
Abstract
The hydroxylation of promazine, chlorpromazine, chlorproethazine, triflu-promazine and promethazine by a rat liver preparation is described. It is concluded that promazine is converted to 3-hydroxypromazine by this system.Keywords
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