Nerve Growth Factor: Stimulation of Regenerative Growth of Central Noradrenergic Neurons
- 17 March 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 175 (4027), 1251-1253
- https://doi.org/10.1126/science.175.4027.1251
Abstract
The growth of new axonal sprouts was studied from transected, ascending noradrenergic axons into transplants of iris tissue in the caudal hypothalamus of the rat. A single intraventricular injection of nerve growth factor, given at the time of axonal damage, resulted in an increased formation and growth of new noradrenaline sprouts 7 days later. The effect seemed to be proportional to the administered dose of nerve growth factor.Keywords
This publication has 6 references indexed in Scilit:
- Quantitative histological analysis of the cerebellar cortex in the catBrain Research, 1971
- Development and growth of axonal sprouts from noradrenaline and 5-hydroxytryptamine neurones in the rat spinal cordBrain Research, 1971
- Growth of central catecholamine neurones into smooth muscle grafts in the rat mesencephalonBrain Research, 1971
- Evidence for regenerative axon sprouting of central catecholamine neurons in the rat mesencephalon following electrolytic lesionsBrain Research, 1971
- Nerve growth factor.Physiological Reviews, 1968
- EFFECTS OF THE EXTRACT OF THE MOUSE SUBMAXILLARY SALIVARY GLANDS ON THE SYMPATHETIC SYSTEM OF MAMMALS*Annals of the New York Academy of Sciences, 1960