Structural Determinants in Human DNA Polymerase γ Account for Mitochondrial Toxicity from Nucleoside Analogs
- 1 May 2003
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 329 (1), 45-57
- https://doi.org/10.1016/s0022-2836(03)00405-4
Abstract
No abstract availableKeywords
This publication has 62 references indexed in Scilit:
- Differential Incorporation and Removal of Antiviral Deoxynucleotides by Human DNA Polymerase γJournal of Biological Chemistry, 2001
- How E. coli DNA polymerase I (klenow fragment) distinguishes between deoxy- and dideoxynucleotidesJournal of Molecular Biology, 1998
- Cloning and Characterization of the Human Mitochondrial DNA Polymerase, DNA Polymerase γGenomics, 1996
- Efficient Incorporation of Anti-HIV Deoxynucleotides by Recombinant Yeast Mitochondrial DNA PolymerasePublished by Elsevier ,1995
- Deoxynucleoside Triphosphate and Pyrophosphate Binding Sites in the Catalytically Competent Ternary Complex for the Polymerase Reaction Catalyzed by DNA Polymerase I (Klenow Fragment)Published by Elsevier ,1995
- Locations of Anti-AIDS Drug Binding Sites and Resistance Mutations in the Three-dimensional Structure of HIV-1 Reverse TranscriptaseJournal of Molecular Biology, 1994
- Sequence analysis of an HIV‐1 isolate which displays unusually high‐level AZT resistance in vitroJournal of Medical Virology, 1992
- A mutant of DNA polymerase I (Klenow fragment) with reduced fidelityBiochemistry, 1991
- An attempt to unify the structure of polymerasesProtein Engineering, Design and Selection, 1990
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976