Pathogenic microbial flora of genital ulcers in Sheffield with particular reference to herpes simplex virus and Haemophilus ducreyi.
- 1 December 1982
- journal article
- research article
- Published by BMJ in Sexually Transmitted Infections
- Vol. 58 (6), 377-380
- https://doi.org/10.1136/sti.58.6.377
Abstract
The pathogenic microbial flora of genital ulcers in 161 (80 men and 81 women) unselected patients was studied prospectively. In only 1 case was Treponema pallidum responsible; herpes simplex virus was considered the cause of 130 (80.8%) genital ulcers. H. ducreyi was isolated from 46 (28.6%) patients, most commonly as a secondary pathogen in herpetic lesions. Two or more pathogens were isolated from the ulcers in 67 (41.6%) patients; no pathogens were isolated in 21 (13%) patients. These results indicate an urgent need for antiviral treatment to reduce the local reservoir of genital herpes. They also challenge traditional concepts about the prevalence of H. ducreyi in Britain and call for a reappraisal of its role in the causation of genital ulcers.This publication has 20 references indexed in Scilit:
- Incidence of herpes simplex virus types 1 and 2 isolated in patients with herpes genitalis in Sheffield.Sexually Transmitted Infections, 1982
- Characterisation of an Unusual Bacterium Isolated from Genital UlcersJournal of Medical Microbiology, 1982
- Chancroid in Sheffield. A report of 22 cases diagnosed by isolating Haemophilus ducreyi in a modified medium.Sexually Transmitted Infections, 1981
- Genital ulcers in Kenya. Clinical and laboratory study.Sexually Transmitted Infections, 1981
- Epidemiologic, Clinical, Laboratory, and Therapeutic Features of an Urban Outbreak of Chancroid in North AmericaClinical Infectious Diseases, 1980
- TEM-type beta-lactamase production in Haemophilus ducreyiAntimicrobial Agents and Chemotherapy, 1980
- Rising incidence of chancroid in Rotterdam. Epidemiological, clinical, diagnostic, and therapeutic aspects.Sexually Transmitted Infections, 1979
- EPIDEMIC OF CHANCROID IN GREENLAND 1977-78The Lancet, 1979
- A Taxonomic Study of the Genus Haemophilus, with the Proposal of a New SpeciesJournal of General Microbiology, 1976
- V.D.R.L. Chancroid StudiesJournal of Investigative Dermatology, 1956