The Influence of Diet Composition on Vitamin B12 Activity in Mice

Abstract

Variations in dietary composition with regard to fat, carbohydrate and protein have been shown to have an influence on vitamin B₁₂ activity in the growing mouse. A decrease in the fat level of the diet intensifies the growth retardation due to a deficiency of vitamin B₁₂. This growth retardation may be partially corrected by the feeding of fat or by the administration of vitamin B₁₂. These effects are intensified by increases in the protein level of the diet.