Linoleic acid in multiple sclerosis: Failure to show any therapeutic benefit
- 29 January 2009
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 58 (1), 53-58
- https://doi.org/10.1111/j.1600-0404.1978.tb02859.x
Abstract
The effect of a dietary supplement with linoleic acid (LA) was studied in 76 patients with MS [multiple sclerosis]. No effect of this supplement was detected on the progression of neurological findings, the relapse rate or the severity of relapses. Oral supplementation with a linoleic acid preparation did raise the blood level of LA in these patients. No reduction in the linoleic acid blood levels associated with acute relapses of MS was demonstrated during this study.This publication has 7 references indexed in Scilit:
- Trail of polyunsaturated fatty acids in non-relapsing multiple sclerosis.BMJ, 1977
- LINOLEIC ACID IN MULTIPLE SCLEROSISThe Lancet, 1975
- Fat Deficiency in Rats during Development of the Central Nervous System and Susceptibility to Experimental Allergic EncephalomyelitisJournal of Nutrition, 1975
- Double-blind Trial of Linoleate Supplementation of the Diet in Multiple SclerosisBMJ, 1973
- Linoleate metabolism in multiple sclerosisJournal of Neurology, Neurosurgery & Psychiatry, 1971
- Further notes on disability evaluation in multiple sclerosis, with scale modificationsNeurology, 1965
- PROBLEMS OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS: REPORT BY THE PANEL ON THE EVALUATION OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSISAnnals of the New York Academy of Sciences, 1965