Abstract
The roles played by the blood clotting system and by fibrinolysis in the haemostatic balance are discussed. The significance of the tissue thromboplastin and the tissue activator of plasminogen for local haemostasis is emphasized, and their relation to anticoagulant therapy considered. Problems specific for coronary thrombosis, cerebral thrombosis and cerebral haemorrhage have been mentioned. * Presented in part at the Fifth Congress of the International Society of Internal Medicine, Philadelphia, April 23—26, 1958. ** Aided by grants from the Josiah Macy, Jr. Foundation, New York, and The National Danish Association against Rheumatic Diseases, Copenhagen.