Relationship between Blood Stasis Syndrome Score and Cardioankle Vascular Index in Stroke Patients
Open Access
- 1 January 2012
- journal article
- research article
- Published by Hindawi Limited in Evidence-Based Complementary and Alternative Medicine
- Vol. 2012, 1-7
- https://doi.org/10.1155/2012/696983
Abstract
Blood stasis syndrome (BSS) in traditional Asian medicine has been considered to correlate with the extent of atherosclerosis, which can be estimated using the cardioankle vascular index (CAVI). Here, the diagnostic utility of CAVI in predicting BSS was examined. The BSS scores and CAVI were measured in 140 stroke patients and evaluated with respect to stroke risk factors. Receiver operating characteristic (ROC) curve analysis was used to determine the diagnostic accuracy of CAVI for the diagnosis of BSS. The BSS scores correlated significantly with CAVI, age, and systolic blood pressure (SBP). Multiple logistic regression analysis showed that CAVI was a significant associate factor for BSS (OR 1.55,) after adjusting for the age and SBP. The ROC curve showed that CAVI and age provided moderate diagnostic accuracy for BSS (area under the ROC curve (AUC) for CAVI, 0.703,; AUC for age, 0.692,). The AUC of the “CAVI+Age,” which was calculated by combining CAVI with age, showed better accuracy (0.759,) than those of CAVI or age. The present study suggests that the CAVI combined with age can clinically serve as an objective tool to diagnose BSS in stroke patients.
Keywords
Funding Information
- Kyung Hee University (KHU-20100672)
This publication has 20 references indexed in Scilit:
- ROC Analysis of the Accuracy of Noncycloplegic Retinoscopy, Retinomax Autorefractor, and SureSight Vision Screener for Preschool Vision ScreeningInvestigative Opthalmology & Visual Science, 2011
- Use of cardio‐ankle vascular index in chronic dialysis patientsEuropean Journal of Clinical Investigation, 2010
- Noninvasive indices of arterial stiffness in hemodialysis patientsHypertension Research, 2009
- Study of the relationship between carotid intima-media thickness and traditional Chinese medicine syndrome of dyslipidemiaChinese Journal of Integrated Medicine, 2009
- Comparison of Atherosclerotic Indicators between Cardio Ankle Vascular Index and Brachial Ankle Pulse Wave VelocityAngiology, 2008
- A Proteomic Approach for the Diagnosis of‘Oketsu’(blood stasis), a Pathophysiologic Concept of Japanese Traditional (Kampo) MedicineEvidence-Based Complementary and Alternative Medicine, 2008
- [Review of clinical and experimental studies on treatment of atherosclerosis with expelling phlegm and relieving blood stasis principle].2006
- Evidence‐Based Reconstruction of Kampo Medicine: Part II—The Concept of ShoEvidence-Based Complementary and Alternative Medicine, 2004
- Effects of Keishi-bukuryo-gan on vascular function and hemorheological factors in spontaneously diabetic (WBN/kob) ratsPhytomedicine, 2004
- Slopes of a Receiver Operating Characteristic Curve and Likelihood Ratios for a Diagnostic TestAmerican Journal of Epidemiology, 1998