ERYTHROPLASIA is a rare disease and was first described in 1893 by Fournier and Darier.1Since Queyrat's2studies in 1911, the disease has been known as erythroplasia of Queyrat. Sulzberger and Satenstein,3in 1933, reported the first case in the American literature. Approximately 50 additional cases have since been presented at various dermatologic societies in this country, in addition to reports by Stiles4and by Irgang and Alexander.5 In spite of the rarity of cases, there has been considerable discussion concerning this disease. It is our purpose in this paper to report our observations in 10 cases. We intend to show that in these instances there was no clinical or microscopic evidence of malignancy or premalignancy and that lesions develop not only on mucous membranes but also on glabrous skin. Suggestions as to therapy also are offered. The 10 patients reported here presented typical clinical