Human Monoclonal Antibody Against a gag-Coded Protein of Human Immunodeficiency Virus Produced by a Stable EBV-Transformed Cell Clone
- 1 February 1989
- journal article
- research article
- Published by Mary Ann Liebert Inc in AIDS Research and Human Retroviruses
- Vol. 5 (1), 73-78
- https://doi.org/10.1089/aid.1989.5.73
Abstract
An EBV-transformed lymphoblastoid B cell clone (A12) derived from peripheral blood lymphocytes of an HIV-1-infected individual is described. The immunoglobulin isotype produced by this clone was IgM, and Southern blot analysis of immunoglobulin gene rearrangement showed a monoclonal pattern. The A12 monoclonal antibody was specific for the p24 product of the HIV-1 gag gene. This clone is now in continuous culture for more than 8 months and no changes in its biologic properties have been observed.This publication has 18 references indexed in Scilit:
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