Impaired executive functioning in young adults born very preterm
- 18 May 2007
- journal article
- research article
- Published by Cambridge University Press (CUP) in Journal of the International Neuropsychological Society
- Vol. 13 (04), 571-581
- https://doi.org/10.1017/s1355617707070725
Abstract
Individuals born very preterm (VPT) are at increased risk of perinatal brain injury and long-term cognitive and behavioral problems. Executive functioning, in particular, has been shown to be impaired in VPT children and adolescents. This study prospectively assessed executive function in young adults who were born VPT (<33 weeks of gestation) [n = 61; mean age, 22.25 (±1.07) years; range, 20.62–24.78 years] and controls [n = 64; mean age, 23.20 (±1.48) years; range, 19.97–25.46 years]. Tests used comprised the Wechsler Abbreviated Scale of Intelligence (WASI), the Hayling Sentence Completion Test (HSCT), the Controlled Oral Word Association Test (COWAT), the Animal and Object test, the Trail-Making Test (TMT), and the Test of Attentional Performance (TAP). VPT participants showed specific executive function impairments in tasks involving response inhibition and mental flexibility, even when adjusting for IQ, gender, and age. No significant associations were observed between executive function test scores and perinatal variables or neonatal ultrasound classification. The results suggest that, although free from major physical disability, VPT young adults perform worse than controls on tasks involving selective aspects of executive processing, such as mental flexibility and response inhibition. (JINS, 2007, 13, 571–581.)Keywords
This publication has 66 references indexed in Scilit:
- Neonatal MRI to Predict Neurodevelopmental Outcomes in Preterm InfantsNew England Journal of Medicine, 2006
- Grades I-II intraventricular hemorrhage in extremely low birth weight infants: Effects on neurodevelopmentThe Journal of Pediatrics, 2006
- Altered functional neuroanatomy of response inhibition in adolescent males who were born very pretermDevelopmental Medicine and Child Neurology, 2006
- Outcome of low birthweight in China: A 16‐year longitudinal studyActa Paediatrica, 2005
- Cognitive development following early brain injury: evidence for neural adaptationTrends in Cognitive Sciences, 2005
- Defining the nature of the cerebral abnormalities in the premature infant: a qualitative magnetic resonance imaging studyThe Journal of Pediatrics, 2003
- Perinatal morbidity, mild motor delay, and later school outcomesDevelopmental Medicine and Child Neurology, 2003
- HRQL and severity of brain ultrasound findings in a cohort of adolescents who were born pretermJournal of Adolescent Health, 2002
- Attention Deficits in Children with < 750 gm Birth WeightChild Neuropsychology, 1998
- Memory and Processing Speed in Preterm Children at Eleven Years: A Comparison with Full-TermsChild Development, 1996