INVITRO STUDIES ON H-2 LINKED UNRESPONSIVENESS TO SYNTHETIC POLYPEPTIDE ANTIGENS .2. INDUCTION OF SUPPRESSOR CELLS IN BOTH RESPONSIVE AND UNRESPONSIVE MICE TO (T,G)-A-L AND GAT10
- 1 January 1977
- journal article
- research article
- Vol. 32 (3), 301-308
Abstract
Antigen-specific T[thymus-derived]-suppressor cells can be induced in vitro from unprimed lymphoid cells of high responder (C57BL/10) and low responder (B10.Br, B10.A, CBA) mice to (T,G)-A-L [synthetic polypeptide containing tyrosine, glutamic acid, alanine and lysine] and high responder (B10, B10.A) and non-responder (B10.G, DBA/1) mice to GAT10 [synthetic polypeptide containing glutamic acid, alanine and 10% tyrosine]. The suppressor cells induced from high and low or non-responder mice appear identical in efficiency, in the antigen concentration required for induction and in their induction kinetics.This publication has 6 references indexed in Scilit:
- Suppressor cell induction in vitro. I. Kinetics of induction of antigen‐specific suppressor cellsEuropean Journal of Immunology, 1976
- Suppressor cell induction in vitro. II. Cellular requirements of suppressor cell inductionEuropean Journal of Immunology, 1976
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- A Cellular Basis for Genetically Controlled Immunologic Unresponsiveness in Mice: Tolerance Induction in T-CellsProceedings of the National Academy of Sciences, 1973