Amino Acid Sequence around the Active Site of Two Class I Fructose‐1,6‐Bisphosphate Aldolases from Staphylococci

Abstract
The amino acid sequences of a 26‐residue segment containing the active‐site lysyl residue of the class I fructose‐1,6‐bisphosphate aldolases from Staphylococcus aureus and Staphylococcus epidermidis have been determined. The sequence homology within the active sites between these enzymes and those from several eucaryotic class I aldolases showed a maximum of 21%. The similarity may indicate the origin of both procaryotic and eucaryotic class I aldolases from a common ancestor.