A FRAME-SHIFT MUTATION INVOLVING THE ADDITION OF TWO BASE PAIRS IN THE LYSOZYME GENE OF PHAGE T4
Open Access
- 1 December 1966
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 56 (6), 1692-1698
- https://doi.org/10.1073/pnas.56.6.1692
Abstract
The primary structure of the lysozyme of the double-mutant strain eJ17eJ44 differs from that of the wild-type strain by a sequence of 5 amino-acids and the insertion of an additional amino-acid next to the altered 5. The mutation eJ17 results in the addition of 2 bases. The acridine dye proflavine causes the insertion of a base, the deletion of a base and the insertion of 2 bases. The lysozyme of the eJ17eJ44 strain was identical to that for the eJ42eJ44 strain except for the addition of an amino acid.This publication has 4 references indexed in Scilit:
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- Heteroduplex heterozygotes in bacteriophage T4 involving mutations of various dimensions.Proceedings of the National Academy of Sciences, 1966
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- Agar Layer Method for Production of High Titer Phage Stocks.Experimental Biology and Medicine, 1951