Intestinal absorption of dietary carotenoids
- 29 December 2006
- journal article
- review article
- Published by Wiley in Molecular Nutrition & Food Research
- Vol. 51 (1), 107-115
- https://doi.org/10.1002/mnfr.200600145
Abstract
The assessment of carotenoid bioavailability has long been hampered by the limited knowledge of their absorption mechanisms. However, recent reports have elucidated important aspects of carotenoid digestion and absorption. Disruption of food matrix and increasing amounts of fat seem to enhance the absorption of carotenes to a larger extent than that of xanthophylls. Comparing different carotenoid species, xanthophylls seem to be more easily released from the food matrix and more efficiently micellized than the carotenes. On the other hand, carotenes are more efficiently taken up by the enterocytes. However, carotenoid emulsification and micellization steps are largely affected by the food matrix and dietary components, being the main determinant of carotenoid bioavailability from foodstuffs. Although the intestinal uptake of carotenoids has been thought to occur by simple diffusion, recent studies reported the existence of receptor‐mediated transport of carotenoids in enterocytes. Comparisons between the intestinal absorption of a wide array of carotenoids would be useful to elucidate the absorption mechanism of each carotenoid species, in view of the recent indications that intestinal carotenoid uptake may involve the scavenger receptor class B type I and possibly other epithelial transporters. The unraveling of the whole mechanism underlying the absorption of carotenoids will be the challenge for future studies.Keywords
This publication has 84 references indexed in Scilit:
- Plasma appearance of labeled β-carotene, lutein, and retinol in humans after consumption of isotopically labeled kaleJournal of Lipid Research, 2005
- Challenges to understanding and measuring carotenoid bioavailabilityBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2004
- Increased intake of fruit and vegetables and a low‐fat diet, with and without low‐fat plant sterol‐enriched spread consumption: effects on plasma lipoprotein and carotenoid metabolismJournal of Human Nutrition and Dietetics, 2004
- Comparison of plasma responses in human subjects after the ingestion of 3R,3R′-zeaxanthin dipalmitate from wolfberry (Lycium barbarum) and non-esterified 3R,3R′-zeaxanthin using chiral high-performance liquid chromatographyBritish Journal of Nutrition, 2004
- Lycopene and β-carotene are bioavailable from lycopene ‘red’ carrots in humansEuropean Journal of Clinical Nutrition, 2004
- Niemann-Pick C1 Like 1 Protein Is Critical for Intestinal Cholesterol AbsorptionScience, 2004
- Plasma response to a single dose of dietary β-cryptoxanthin esters from papaya (Carica papayaL.) or non-esterified β-cryptoxanthin in adult human subjects: a comparative studyBritish Journal of Nutrition, 2003
- Influence of Dietary Fat on β-Carotene Absorption and Bioconversion into Vitamin aNutrition Reviews, 2002
- Estimation of carotenoid bioavailability from fresh stir-fried vegetables using an in vitro digestion/Caco-2 cell culture modelThe Journal of Nutritional Biochemistry, 2000
- Spreads enriched with three different levels of vegetable oil sterols and the degree of cholesterol lowering in normocholesterolaemic and mildly hypercholesterolaemic subjectsEuropean Journal of Clinical Nutrition, 1999