Phase II trial of Didemnin B in patients with advanced renal cell carcinoma
- 1 November 1990
- journal article
- conference paper
- Published by Springer Nature in Investigational New Drugs
- Vol. 8 (4), 391-392
- https://doi.org/10.1007/bf00198598
Abstract
Twenty-three patients with advanced renal cell cancer were treated with Didemnin B. One partial response was achieved (5%) in 21 evaluable patients. An allergic reaction was noted in four patients including one patient with anaphylaxis. Didemnin B is not recommended in the treatment of renal cell carcinoma.Keywords
This publication has 3 references indexed in Scilit:
- Phase I clinical and pharmacokinetic investigation of didemnin B, a cyclic depsipeptideEuropean Journal of Cancer and Clinical Oncology, 1988
- Didemnins: Antiviral and Antitumor Depsipeptides from a Caribbean TunicateScience, 1981
- Reporting results of cancer treatmentCancer, 1981