Urinary Oestrogen and Plasma Human Placental Lactogen as Initial Screening Tests for a Placental Sulphatase Deficiency

Abstract
As a result of routine screening of ante-natal patients by urinary total oestrogens and plasma human placental lactogen (HPL) from 35 weeks, a rare placental sulphatase deficiency was indicated which was later confirmed by in vitro studies of placental enzyme activities.