Metabolic polymorphisms
- 1 January 1993
- journal article
- Published by Elsevier in Pharmacology & Therapeutics
- Vol. 57 (2-3), 129-160
- https://doi.org/10.1016/0163-7258(93)90053-g
Abstract
No abstract availableKeywords
This publication has 237 references indexed in Scilit:
- Human cytochrome P-450 enzymesLife Sciences, 1992
- Metabolic polymorphisms affecting activation of toxic and mutagenic arylaminesTrends in Pharmacological Sciences, 1992
- Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemiaThe Journal of Pediatrics, 1991
- Tolbutamide and phenytoin hydroxylations by cDNA-expressed human liver cytochrome P4502C9Biochemical and Biophysical Research Communications, 1991
- Pharmacokinetics of Nifedipine Slow Release Tablet in Mexican Subjects: Further Evidence for an Oxidation PolymorphismThe Journal of Clinical Pharmacology, 1989
- A N-methyltransferase in human brain catalyses N-methylation of 1,2,3,4-tetrahydroisoquinoline into N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of a dopaminergic neurotoxin, N-methylisoquinolinium ionBiochemical and Biophysical Research Communications, 1989
- MPTP, the neurotoxin inducing parkinson's disease, is a potent competitive inhibitor of human and rat cytochrome P450 isozymes (P450bufI, P450db1) catalyzing debrisoquine 4-hydroxylationBiochemical and Biophysical Research Communications, 1987
- The human β3 alcohol dehydrogenase subunit differs from β1 by a cys for Arg-369 substitution which decreases NAD(H) bindingBiochemical and Biophysical Research Communications, 1987
- Nortriptyline and antipyrine clearance in relation to debrisoquine hydroxylation in manLife Sciences, 1980
- Hydrolysis of cocaine in human plasma by cholinesteraseLife Sciences, 1977