Chronic myelogenous leukemia is uncommon in childhood and rare in infancy. The disease seldom occurs in infants less than 6 months of age. In 1933, Cooke1reported 3 cases encountered in the St. Louis Children's Hospital during a period of fifteen years. The patients were 8 years old or older. Poncher, Weir and Limarzi,2in 1942, surveyed the literature and found only 2 cases of myelogenous leukemia which they thought could be considered chronic and in which the disease had its onset in early infancy. These 2 cases had been reported by Solmitz3and Malmberg4in 1924. Poncher, Weir and Limarzi reported 1 case of their own in which the disease was thought to be of congenital origin. The diagnosis was made when the infant was 6 weeks old. Death occurred at the age of slightly more than 3 months; hence the child was under observation