Morphogenesis in Trichoderma : Suppression of Photoinduction by 5-Fluorouracil
- 11 February 1966
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 151 (3711), 696-698
- https://doi.org/10.1126/science.151.3711.696
Abstract
Sporulation in the fungus Trichoderma viride is inducible with a short light pulse. 5-Fluorouracil applied prior to photoinduction and removed thereafter suppressed sporulation without greatly aflecting growth. This compound also halved the rate of incorporation of uracil-C14 into RNA but did not change the ratio of uridylic to cytidylic acid. The effect of 5-fluorouracil was counteracted by uracil but not by thymidine. This supports the hypothesis that 5-fluorouracil affects RNA rather than DNA.This publication has 9 references indexed in Scilit:
- Characteristics of 5-fluorouracil-induced synthesis of alkaline phosphataseJournal of Molecular Biology, 1965
- Characterization of messenger RNA in sporulating Bacillus cereusJournal of Molecular Biology, 1965
- A New Method for the Determination of the Base Composition of Ribonucleic AcidJournal of Biological Chemistry, 1963
- Ribonucleic Acid Synthesis in the Bud Essential Component of Floral Induction in XanthiumPlant Physiology, 1962
- Effects of Fluoropyrimidines on the Synthesis of Bacterial Proteins and Nucleic AcidsJournal of Biological Chemistry, 1960
- Incorporation of Uracil-2-C14 into the Nucleic Acids of Neurospora crassaJournal of Biological Chemistry, 1960
- Inhibition of Photoperiodic Induction by 5-FluorouracilPlant Physiology, 1960
- Massive Incorporation of 5-Fluorouracil into a Bacterial Ribonucleic AcidNature, 1959
- Studies on Fluorinated PyrimidinesPublished by Elsevier ,1959