Biochemical Evidence of Nutritional Status
- 1 October 1952
- journal article
- research article
- Published by American Physiological Society in Physiological Reviews
- Vol. 32 (4), 431-448
- https://doi.org/10.1152/physrev.1952.32.4.431
Abstract
The assessment of nutritional status is a separate problem for each individual nutrient, and the type of test appropriate for one nutrient may fail completely for another. With a given nutrient a single type of measurement may be suited to one purpose and not another. The urinary excretion of thiamine may describe the thiamine status of a large group quite adequately, yet the finding that a particular person has excreted only 50ug. thiamine in the past 24 hrs. is not very helpful. The blood level of vit. A is a good measure of vit. A status with incipient deficiency, but it completely fails to measure the vit. A stored in the liver. In studying and treating obesity the one dominant fact is the wt. of the patient. For the study and treatment of other nutritional problems the amt. of a particular vit. in the body and how this relates to the most desirable amt. is equally basic. Limitation of the discussion to 3 nutrients (ascorbic acid, thiamine, and riboflavin) exclude many possibilities for biochemical evaluation of status. There may remain to be discovered innumerable chemical means for measuring adequacy of status in regard to each of the nutrients. The author stresses the significance of tissue concentrations, and indicates how these relate to performance, intake, excretion, blood levels, etc.Keywords
This publication has 26 references indexed in Scilit:
- The Relation of the Blood Level of Ascorbic Acid to the Tissue Concentrations of This Vitamin and to the Histology of the Incisor Teeth in the Guinea PigJournal of Nutrition, 1944
- SUBCLINICAL VITAMIN DEFICIENCY V. THE ASSAY OF SUBCLINICAL THIAMIN DEFICIENCYAnnals of Internal Medicine, 1944
- Riboflavin and Thiamine Interrelation-Ships in Rats and in ManJournal of Nutrition, 1943
- Observations on Induced Riboflavin Deficiency and the Riboflavin Requirement of ManJournal of Nutrition, 1943
- THE URINARY EXCRETION OF THIAMINE AS AN INDEX OF THE NUTRITIONAL LEVEL: ASSESSMENT OF THE VALUE OF A TEST DOSEJournal of Clinical Investigation, 1942
- THE MECHANISM OF THE EXCRETION OF VITAMIN C BY THE HUMAN KIDNEY AT LOW AND NORMAL PLASMA LEVELS OF ASCORBIC ACID 1Journal of Clinical Investigation, 1940
- DISTRIBUTION OF ASCORBIC ACID IN THE BLOOD AND ITS NUTRITIONAL SIGNIFICANCEJournal of Clinical Investigation, 1940
- The Concentration of Vitamin B1 in the Tissues of the RatJournal of Nutrition, 1939
- Vitamin B1 and cocarboxylase in animal tissuesBiochemical Journal, 1938
- Studies of Crystalline Vitamin BJournal of Nutrition, 1935