Synthesis of novel cyclic protease inhibitors using Grubbs olefin metathesis
- 1 February 1998
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 8 (4), 357-360
- https://doi.org/10.1016/s0960-894x(98)00025-0
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Total Synthesis of the Cyclic Biphenyl Ether Peptides K-13 and OF4949-III via SNAr Macrocyclization of Peptidyl Ruthenium π-Arene ComplexesJournal of the American Chemical Society, 1997
- Novel Cyclic Biphenyl Ether Peptide β-Strand Mimetics and HIV-Protease InhibitorsJournal of the American Chemical Society, 1997
- A Novel Bicyclic Enzyme Inhibitor as a Consensus Peptidomimetic for the Receptor-Bound Conformations of 12 Peptidic Inhibitors of HIV-1 ProteaseJournal of the American Chemical Society, 1996
- Synthesis of Conformationally Restricted Amino Acids and Peptides Employing Olefin MetathesisJournal of the American Chemical Society, 1995
- Design, Synthesis, and Conformational Analysis of a Novel Macrocyclic HIV-Protease InhibitorJournal of Medicinal Chemistry, 1994
- Multiple Highly Diverse Structures Complementary to Enzyme Binding Sites: Results of Extensive Application of a de Novo Design Method Incorporating Combinatorial GrowthJournal of the American Chemical Society, 1994
- Synthesis and biological activity of new conformationally restricted analogues of pepstatin*International Journal of Peptide and Protein Research, 1992
- The asymmetric synthesis of .alpha.-amino acids. Electrophilic azidation of chiral imide enolates, a practical approach to the synthesis of (R)- and (S)-.alpha.-azido carboxylic acidsJournal of the American Chemical Society, 1990
- Structure and refinement at 1.8 Å resolution of the aspartic proteinase from Rhizopus chinensisJournal of Molecular Biology, 1987
- On the size of the active site in proteases. I. PapainBiochemical and Biophysical Research Communications, 1967