Phenytoin-Induced Teratogenesis: A Mouse Model
- 30 January 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 211 (4481), 483-484
- https://doi.org/10.1126/science.7455686
Abstract
Malformations associated with the fetal hydantoin syndrome have been reproduced in a mouse model. The occurrence of these defects was correlated with maternal serum concentrations, but not with maternal or fetal genotype or the presence of a seizure disorder.This publication has 13 references indexed in Scilit:
- Phenytoin (dilantin)‐induced cleft lip and palate in a/j mice: A scanning and transmission electron microscopic studyThe Anatomical Record, 1979
- Risks to the offspring of women treated with hydantoin anticonvulsants, with emphasis on the fetal hydantoin syndromeThe Journal of Pediatrics, 1976
- The fetal hydantoin syndromeThe Journal of Pediatrics, 1975
- The Teratogenic Risk of Antiepileptic DrugsEpilepsia, 1975
- Infants Exposed in Utero to Antiepileptic DrugsAmerican Journal of Diseases of Children, 1974
- Digital hypoplasia and anticonvulsants during gestation: A teratogenic syndrome?The Journal of Pediatrics, 1974
- The Dysmorphogenic Potential of PhenytoinDrugs, 1974
- Diphenylhydantoin and Selected Congenital MalformationsNew England Journal of Medicine, 1973
- Relation of dosage and time of administration of diphenylhydantoin to its teratogenic effect in miceTeratology, 1969
- Teratogenic Effects of Diphenylhydantoin in Swiss-Webster and A/J MiceExperimental Biology and Medicine, 1968