Pulsatile Growth Hormone Secretion: Suppression by Hypothalamic Ventromedial Lesions and by Long-Acting Somatostatin
- 8 November 1974
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 186 (4163), 538-540
- https://doi.org/10.1126/science.186.4163.538
Abstract
Sequential blood samples, obtained from freely behaving, nonstressed male rats, showed a pulsatile pattern of growth hormone secretion with a mean interval between peaks of 68 minutes. The bursts of secretion were blocked by lesions of the hypothalamic ventromedial nuclei and by administration of a longacting preparation of synthetic somatostatin.Keywords
This publication has 19 references indexed in Scilit:
- INHIBITION OF GROWTH HORMONE RELEASE IN HUMANS BY SOMATOSTATIN.Journal of Clinical Endocrinology & Metabolism, 1973
- The Nocturnal Rise of Human Prolactin Is Dependent on SleepJournal of Clinical Endocrinology & Metabolism, 1973
- Neural Regulation of Growth Hormone SecretionNew England Journal of Medicine, 1973
- ACTH and Cortisol Secretory Patterns in ManJournal of Clinical Endocrinology & Metabolism, 1973
- Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth HormoneScience, 1973
- Daily Variation in Rat Growth Hormone Concentration and the Effect of Stress on PeriodicityNeuroendocrinology, 1973
- Human Prolactin: 24-Hour Pattern with Increased Release during SleepScience, 1972
- Evidence for a Periodic Release of LH in Castrated Male and Female Rats1Endocrinology, 1972
- Hypothalamic Stimulation of Growth Hormone SecretionScience, 1968
- Some Studies of the Protein-Binding of Steroids and Their Application to the Routine Micro and Ultramicro Measurement of Various Steroids in Body Fluids by Competitive Protein-Binding Radioassay1Journal of Clinical Endocrinology & Metabolism, 1967