Plasma free fatty acids in dogs treated with Triton WR-1339
- 30 November 1961
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 201 (6), 1035-1040
- https://doi.org/10.1152/ajplegacy.1961.201.6.1035
Abstract
Dogs fed a regular diet were given intravenously 250 mg of Triton WR-1339 (a nonionic surface active agent) every 4th day. When sustained lipemia developed, their plasma free fatty acid (FFA) response to epinephrine and glusose was studied and compared with that of normal animals. The time course of the rise (epinephrine) or fall (glucose) of the plasma FFA was similar in the two groups of animals. The Triton-treated dogs had, however, plasma FFA levels twice as high as normals. Plasma FFA, which in control dogs were bound principally to albumin, were mostly associated in the Triton-treated animals with the low-density ß-lipoproteins. A partial shift of FFA from albumin to ß-lipoproteins could be produced in vitro by addition of Triton to normal canine serum.Keywords
This publication has 10 references indexed in Scilit:
- TRITON HYPERLIPEMIA IN DOGSThe Journal of Experimental Medicine, 1961
- Recombination with lipids of the lipid-free protein from canine serum (d 1.063-1.2 1, α1) lipoproteinJournal of Lipid Research, 1961
- TRITON HYPERLIPEMIA IN DOGSThe Journal of Experimental Medicine, 1961
- Recombining Capacity toward Lipids of the Protein Moiety of Human Serum α1-LipoproteinJournal of Biological Chemistry, 1960
- THE ESSENTIAL ROLE OF THE ADRENAL CORTEX IN THE RESPONSE OF PLASMA FREE FATTY ACIDS, CHOLES-TEROL, AND PHOSPHOLIPIDS TO EPINEPHRINE INJECTION *JCI Insight, 1960
- ACTH in vitro on Release of Nonesterified Fatty Acids from Adipose Tissues of Adrenalectomized RatsExperimental Biology and Medicine, 1959
- Partition of Unesterified Fatty Acids in Normal and Nephrotic Syndrome Serum and Its Effect on Serum Electrophoretic Pattern1JCI Insight, 1958
- Transport of Fatty AcidsPhysiological Reviews, 1958
- UNESTERIFIED FATTY ACID IN HUMAN BLOOD PLASMA 1JCI Insight, 1956
- A RELATION BETWEEN NON-ESTERIFIED FATTY ACIDS IN PLASMA AND THE METABOLISM OF GLUCOSEJCI Insight, 1956