Determining factor in the capacity of Rous sarcoma virus to induce tumors in mammals.
- 1 March 1966
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 55 (3), 532-538
- https://doi.org/10.1073/pnas.55.3.532
Abstract
Enclosure of the genome of Schmidt-Ruppin strain of RSV [Rous sarcoma virus] within the viral envelope of RAV [Rous associated virus]-l rendered it inactive in tumor induction in newborn hamsters. Among the variants of Bryan strain of RSV coated by RAV-1, RAV-2, and a newly Isolated helper virus CRAV-50), only the last variant produced sarcomas In hamsters. The results are consistent with the hypothesis that the ability of RSV to induce mammalian tumors is determined by the viral envelope.This publication has 18 references indexed in Scilit:
- Analysis of the defectiveness of rous sarcoma virus III. Determining influence of a new helper virus on the host range and susceptibility to interference of RSVVirology, 1965
- INFECTION OF HUMAN AND SIMIAN TISSUE CULTURES WITH ROUS SARCOMA VIRUSProceedings of the National Academy of Sciences, 1964
- Tumors Induced in Primates by Chicken Sarcoma VirusScience, 1963
- THE DEFECTIVENESS OF ROUS SARCOMA VIRUSProceedings of the National Academy of Sciences, 1963
- INDUCTION OF TUMOURS IN SYRIAN HAMSTERS BY 2 VARIANTS OF ROUS SARCOMA VIRUS1963
- TEMPORARY GROWTH OF ROUS SARCOMA (STRAIN MILL HILL) IN NEW‐BORN RATS AND MICE1Acta Pathologica Microbiologica Scandinavica, 1962
- SARCOMAS IN HAMSTERS AFTER INJECTION WITH ROUS CHICKEN TUMOR MATERIALThe Journal of Experimental Medicine, 1962
- Receptor affinities as major determinants of enterovirus tissue tropisms in humansVirology, 1961
- A VIRUS IN CHICK EMBRYOS WHICH INDUCES RESISTANCE IN VITRO TO INFECTION WITH ROUS SARCOMA VIRUSProceedings of the National Academy of Sciences, 1960
- Sarcoma in Albino Rats treated during the Embryonic Stage with Rous VirusNature, 1958