Studies of cytogenetic effects of sodium arsenicals on mammalian cells in vitro
- 1 January 1982
- journal article
- research article
- Published by Wiley in Environmental Mutagenesis
- Vol. 4 (4), 493-498
- https://doi.org/10.1002/em.2860040408
Abstract
The cytotoxic and cytogenetic effect of sodium arsenite and sodium arsenate on Chinese hamster ovary (CHO) cells is reported. Chromosome aberrations were induced with both arsenic compounds. Trivalent arsenic was more clastogenic than pentavalent arsenic. Sodium arsenite was also shown to produce increased sister chromatid exchange in CHO cells and increased chromosome breakage in human lymphocytes.Keywords
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