Renin and Acute Renal Failure: Studies in Man
- 31 January 1970
- Vol. 1 (5691), 253-258
- https://doi.org/10.1136/bmj.1.5691.253
Abstract
Plasma renin concentration was increased, usually appreciably, in 22 out of 25 patients with acute renal failure, the average value being 226 units/litre (mean for normal subjects 8·2 units/1.). The highest renin values were found in the first 10 days of the disease; lower and sometimes normal values were found subsequently. Unequivocal acute tubular necrosis was present in only two of the eight cases examined post mortem. These findings are compatible with Goormaghtigh's proposal that an excess of renin and angiotensin may act within the kidney to produce acute renal failure.Keywords
This publication has 64 references indexed in Scilit:
- Plasma Renin Activity in Acute Renal InsufficiencyNephron, 1969
- RENIN LOCATION IN THE DIFFERENT PARTS OF THE JUXTAGLOMERULAR APPARATUS IN THE CAT KIDNEYActa Pathologica Microbiologica Scandinavica, 1968
- A Light and Electron Microscopic Study of Renal Tubular RegenerationNephron, 1968
- Zur Regulation der Reninsekretion durch AngiotensinKlinische Wochenschrift, 1967
- PERITONEAL DIALYSIS IN HYPERCATABOLIC ACUTE RENAL FAILUREThe Lancet, 1967
- Glycerol Induced Hemoglobinuric Acute Renal Failure in the RatNephron, 1967
- Regulierung von Glomerulumfiltrat und arteriellem Blutdruck durch den Natriumgradienten an den Macula densa-ZellenKlinische Wochenschrift, 1967
- Renale Hämodynamik und hämorrhagische HypotensionKlinische Wochenschrift, 1966
- Plasma Renin Activity in Acute Tubular Necrosis and Other Renal Diseases Associated with HypertensionCirculation, 1965
- INFLUENCE OF SODIUM LOADING AND SODIUM DEPLETION ON PLASMA-RENIN IN MANThe Lancet, 1963