Increased Mucociliary Transport by Adrenergic Stimulation
- 1 March 1976
- journal article
- research article
- Published by Taylor & Francis in Archives of environmental health
- Vol. 31 (2), 79-82
- https://doi.org/10.1080/00039896.1976.10667194
Abstract
Tracheobronchial clearance of inhaled 6 .mu.m Teflon particles (density 2 g/cm3) tagged with 99mTc was studied in healthy human subjects by external measurement of the radioactivity in the lungs for 2 h. Clearance, salivary secretion, blood pressure and heart rate were determined in 8 subjects after double-blind, s.c. administration of 0.25 mg terbutaline sulfate, a .beta.-adrenoceptor stimulating compound and vehicle, respectively, in a crossover study. Terbutaline produced a marked increase in clearance and a slight increase in heart rate, but had no important effect on salivary secretion or blood pressure. Blood concentrations of catecholamines might be of importance for the regulation of the mucociliary transport rate.This publication has 6 references indexed in Scilit:
- Increased Mucociliary Transport by Cholinergic StimulationArchives of environmental health, 1974
- Mucociliary Function of the Respiratory Tract as Influenced by DrugsRespiration, 1974
- On the production of monodisperse particles with a spinning discJournal of Aerosol Science, 1973
- An Organ Culture Study of the Effect of Drugs on the Secretory Activity of the Human Bronchial Submucosal GlandClinical Science, 1972
- A simple method for nucledic tagging of monodisperse fluorocarbon resin particlesThe International Journal of Applied Radiation and Isotopes, 1971
- Production of 7μ monodisperse fluorocarbon resin particles tagged with 18FThe International Journal of Applied Radiation and Isotopes, 1971