Inhibition of Bone Resorption in Vitro by a Cartilage-Derived Anticollagenase Factor
- 24 March 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 199 (4335), 1342-1345
- https://doi.org/10.1126/science.204011
Abstract
A cartilage-derived factor containing a specific collagenous inhibitor was found to block reversibly parathyroid hormone-stimulated 45Ca release from fetal rat bone in vitro. Morphologic and quantitative histometric examination revealed that this factor modulates osteoclastic activities.Keywords
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