Beziehungen des Schlaf- und Wachrhythmus zum Noradrenalin- und Serotoningehalt im Zentralnervensystem von Hamstern

Abstract

Estimations of the daily changes of the serotonin and norepinephrine contents in the central nervous system, of male hamsters, were made from 9 a.m. to 11 p.m. During sleep a higher serotonin level and a small decrease in the amount of norepinephrine was found compared with the 7 p.m. value. The lowest serotonin level was at the time of the highest spontaneous motoric activity, between 9 and 11 p.m., both amines were on a high level in equilibrium. The results were discussed in correlation with the ergotropic and trophotropic and trophotropic system and with the possible reasons for natural sleep.