Prevention of Phosphate Stones by Phytate, Phosphate and Hexametaphosphate: Experimental Urolithiasis XV

Abstract
The effects of phytate, phosphate, and hexametaphosphate on stone formation was studied in young adult rats. Stone formation was induced by the implantation into the bladder of a Zn disk. The addition to the standard diet of sodium phytate, ortho-phosphate, or hexametaphosphate prevented the formation of stones of Mg and Ca types. It is suggested that this effect is due to interference with intestinal absorption of Ca and Mg.