Routine diagnosis of human rotaviruses in stools.
Open Access
- 1 February 1978
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 31 (2), 175-178
- https://doi.org/10.1136/jcp.31.2.175
Abstract
Electron microscopy, immune electron microscopy and complement fixation as methods of detecting rotavirus in the stools of young children with gastroenteritis were compared in a blind study during the winter of 1975-6. Complement fixation was the simplest to perform, was as sensitive as the other two, and allowed a quantitative measurement of viral excretion. Absorption of faecal extracts with fetal calf serum usually removed the anticomplementary activity of faecal extracts.Keywords
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